Alaska offers direct flights from Seattle to 95 cities. The most frequent destinations are: Anchorage, Portland, Spokane, Los Angeles and Boise.

Delta offers direct flights from Seattle to 56 cities. The most frequent destinations are: Spokane, Portland, Atlanta, Salt Lake City and Los Angeles.

Southwest offers direct flights from Seattle to 13 cities. The most frequent destinations are: Denver, Oakland, Sacramento, San Jose and Las Vegas.

Frontier offers direct flights from Seattle to 7 cities. The most frequent destinations are: Denver, Ontario, Phoenix, Las Vegas and Los Angeles.

United offers direct flights from Seattle to 7 cities. The most frequent destinations are: San Francisco, Denver, Chicago, Houston and Newark.

American offers direct flights from Seattle to 7 cities. The most frequent destinations are: Dallas, Chicago, Charlotte, Phoenix and Philadelphia.